Declaration on Religious Freedom: Three Developmental Aspects

This article considers key aspects of the Vatican II declaration on religious freedom Dignitatis Humanae and John Courtney Murray’s role in its formulation. This will be done with concern for the broader theological context as exemplified in Thomas Aquinas. After a brief outline of the difficulties Murray faced and their resolution, the discussion moves in four stages: a summary of the key ideas in the document on the relationship between truth and freedom from which the following three ideas receive a focus; the person (dignity and conscience); rights and their evolving context; historical consciousness and its role as a mode and locus of theological reflection. Here, a suggestion is offered about the interrelationship of speculative and practical reason in doctrinal development

Influence of anneal atmosphere on ZnO-nanorod photoluminescent and morphological properties with self-powered photodetector performance

OA Monitor ExerciseEPSR

Factors associated with service use for young adolescents with mental health problems: findings from an Australian longitudinal study

The objective of the study wasto identify factors associated with use of services for adolescent mental health problems in an Australian community-based sample. Logistic regression analysis was conducted on data collected from 636 parents and their adolescent child to identify individual and family variables predicting parent report of service use for mental health problems in the adolescent 12 months later. The services most reported by parents to have been accessed were schoolbased ones. Multivariate analysis found that the following were associated with service use 12 months later: the adolescent being female, parent report of peer problems and hyperactivity, single-parent household, the parent being Australian born, and prior service use by the adolescent. Parental overcontrol was associated with reducedlikelihood of service use at followup. No association was found between service use at follow-up and parent gender, socioeconomic status, number of siblings, parent psychopathology, family social connectedness, and prior service use by the parent. No association was also found for family environment factors, parental attachment, or for the adolescent’s emotional competence or use of social support. The results indicate that families provide a potential target for interventions aimed at increasing use of professional services for adolescent mental health problems

Within-Home versus Between-Home Variability of House Dust Endotoxin in a Birth Cohort

Endotoxin exposure has been proposed as an environmental determinant of allergen responses in children. To better understand the implications of using a single measurement of house dust endotoxin to characterize exposure in the first year of life, we evaluated room-specific within-home and between-home variability in dust endotoxin obtained from 470 households in Boston, Massachusetts. Homes were sampled up to two times over 5–11 months. We analyzed 1,287 dust samples from the kitchen, family room, and baby’s bedroom for endotoxin. We fit a mixed-effects model to estimate mean levels and the variation of endotoxin between homes, between rooms, and between sampling times. Endotoxin ranged from 2 to 1,945 units per milligram of dust. Levels were highest during summer and lowest in the winter. Mean endotoxin levels varied significantly from room to room. Cross-sectionally, endotoxin was moderately correlated between family room and bedroom floor (r = 0.30), between family room and kitchen (r = 0.32), and between kitchen and bedroom (r = 0.42). Adjusting for season, the correlation of endotoxin levels within homes over time was 0.65 for both the bedroom and kitchen and 0.54 for the family room. The temporal within-home variance of endotoxin was lowest for bedroom floor samples and highest for kitchen samples. Between-home variance was lowest in the family room and highest for kitchen samples. Adjusting for season, within-home variation was less than between-home variation for all three rooms. These results suggest that room-to-room and home-to-home differences in endotoxin influence the total variability more than factors affecting endotoxin levels within a room over time

Short-scale turbulent fluctuations driven by the electron-temperature gradient in the national spherical torus experiment

Measurements with coherent scattering of electromagnetic waves in plasmas of the National Spherical Torus Experiment indicate the existence of turbulent fluctuations in the range of wave numbers k(perpendicular to)rho(e)=0.1-0.4, corresponding to a turbulence scale length nearly equal to the collisionless skin depth. Experimental observations and agreement with numerical results from a linear gyrokinetic stability code support the conjecture that the observed turbulence is driven by the electron-temperature gradient.X1155sciescopu

Aptamer biosensing based on metal enhanced fluorescence platform: A promising diagnostic tool

Diagnosis of disease at an early, curable, and reversible stage allows more conservative treatment and better patient outcomes. Fluorescence biosensing is a widely used method to detect biomarkers, which are early indicators of disease. Importantly, biosensing requires a high level of sensitivity. Traditionally, these sensors use antibodies or enzymes as biorecognition molecules; however, these can lack the specificity required in a clinical setting, limiting their overall applicability. Aptamers are short, single stranded nucleotides that are receiving increasing attention over traditional recognition molecules. These exhibit many advantages, such as high specificity, making them promising for ultrasensitive biosensors. Metal enhanced fluorescence (MEF) utilizes plasmonic materials, which can increase the sensitivity of label-based fluorescent biosensors. The fluorescence enhancement achieved by placing metallic nanostructures in close proximity to fluorophores allows for detection of ultra-low biomarker concentrations. Plasmonic biosensors have been successfully implemented as diagnostic tools for a number of diseases, such as cancer, yet reproducible systems exhibiting high specificity and the ability to multiplex remain challenging. Similarly, while aptasensors have been extensively reported, few systems currently incorporate MEF, which could drastically improve biosensor sensitivity. Here, we review the latest advancements in the field of aptamer biosensing based on MEF that have been explored for the detection of a wide variety of biological molecules. While this emerging biosensing technology is still in its infant stage, we highlight the potential challenges and its clinical potential in early diagnosis of diseases